Topical numbing creams can constrict and change tissue texture. To work, most use lidocaine and vasoconstrictors which constrict blood vessels to contribute to the process of numbing. However, once the cream wears off, the skin shifts. This means that if a person gets pierced with a topical numbing cream, it may be crooked or off when it heals.Because of the way the skin shifts and moves, a piercing that is straight on numb tissue can become crooked once the cream has worn off. As a result you should avoid crooked piercings because they won’t heal and if you use a cream it will not matter since most piercings are painless.